How To Fight A Cold

To maximize the amount of allicin fresh garlic should be chopped or crushed and it should be raw. These remedies might help you feel better.

10 Foods That Can Fight Your Cold

Garlic and onions are some of the best foods you can eat to combat symptoms of cold and flu.

How to fight a cold. Feeling stuffy and congested can make a cold feel a lot worse. Youll get 74 milligrams or about what youll find in 6 lozenges in just 3 ounces. Both of these flowering plants have long been used since Egyptian practices for their medicinal treatment of viruses bacteria and fungus.

To get your zinc fill toss back a couple of oysters. And were talking steamy not sexy especially if you take Schaffners. Allicin is what gives garlic its distinctive hot flavor.

5 6 For a cold-fighting tea place ¼ teaspoon of turmeric powder in eight ounces of hot water. Using a nasal irrigator can also help break up congestion which can work to relieve that. Body aches and a low-grade fever are normal but double up on your liquids - water broth and juices - to stay hydrated.

Just dont take any other supplements beyond. Taking Immediate Action 1. Dana Corriel MD and an internist recommends taking a zinc supplement as soon as you notice symptoms of a cold to stave off getting full-blown sick.

Try a delicious cup of ginger tea the next time youre feeling a little under the weather and you might be surprised how much better it makes you feel. Gargling with salt water can help reduce inflammation in your. Cinnamon and honey are two such powerful ingredients which offer plenty of health benefits for the human body.

Heres another tip for folks feeling like the bulk of their body weight has gravitated to their. Or add a bunch on ginger along with your garlic to a steaming cup of bone broth. From A to Zinc.

Its also available in pill form. Both of these flowering plants have long been used since Egyptian practices for their medicinal treatment of viruses bacteria and fungus 8. How to Get Rid of a Cold Fast 1.

Apple cider vinegar Many people are attracted to using apple cider vinegar as a treatment because of its proposed ability to fight off bacteria viruses and other germs. Add an extra pillow. Taking a vitamin C supplement isnt likely to prevent a cold.

Take a hot shower to help with nasal congestion. Theyre the best natural source of zinc. Using nasal irrigation to cleanse the sinus cavities can help get rid of germs and bacteria in this area.

Draw a hot steamy shower. The cold-fighting compound in garlic is thought to be allicin which has demonstrated antibacterial and antifungal properties. To relieve congestion and sinus pressure use hot steamy showers and humidifiers and consider an over-the-counter nasal decongestant.

Fight a Cold with Ginger Ginger is considered a top choice for fighting off colds and relieving cold symptoms. Garlic and onions are some of the best foods you can eat to combat symptoms of cold and flu. Your cold is in full swing and youre feeling knocked out.

Its rich in antioxidants and may provide defense from harmful organisms that cause sickness. Water juice clear broth or warm lemon water with honey helps loosen congestion and prevents dehydration. Use a saline nasal spray.

Drink this mixture often throughout the autumn and winter seasons. Soothe a sore throat. As a gentle food turmeric may also help soothe a sore throat.

Take a hot shower. On average the length of cold duration was cut down by 33 percent which could. However studies show that it may reduce the.

Give that virus a run for its money. Taking your prenatal vitamin which contains vitamin C and zinc is smart even when youre fighting a cold. When one is well a balanced diet with adequate protein promotes well-being and reduces the chance for catching a cold Novey says.

Gargle with salt water if you have a sore throat. 1 day agoThe Indian kitchen is a storehouse of many home remedies and simple foods which we can include in our diet for good health. Your body needs rest to heal.

If you do get a cold listen to what your stomach is. This cinnamon-honey tea is a great way to load up on good health and immunity and fight cold and flu naturally.

Vaginal Bacterial Overgrowth

Symptoms of lactobacillus overgrowth mimic those experienced by women who have a vaginal yeast infection caused by the bacterium Candidas albicans. Vaginal Bacterial Overgrowth - Overview Symptoms Causes Treatment and Prevention.

Bacterial Vaginosis Causes And Risk Factors

Bacterial vaginosis is a vaginal condition that results from an overgrowth of normal bacteria in the vagina.

Vaginal bacterial overgrowth. Having a vaginal discharge can be embarrassing. How common is bacterial vaginosis. Bacterial vaginosis or BV is a vaginal infection caused by an overgrowth of anaerobic bacteria and an organism called Gardnerella vaginalis.

Bacterial vaginosis BV is an overgrowth of a certain type of bacteria in the vagina birth canal. Lactobacillus is a naturally occurring bacteria present within a womans vagina. If youre experiencing vaginal discharge with odor it is very likely that an overgrowth of bacteria is contributing to the cause.

Bacterial vaginosis BV is a common vaginal infection that happens when some normal bacteria that lives in the vagina overgrows causing a bacterial imbalance. This causes a change in the normal vaginal discharge which may become more noticeable or develop a fishy smell. It is a common condition that may or may not cause symptoms.

Anaerobic means the bacteria doesnt need any oxygen to survive or grow. Theres still a lot that experts dont understand about the condition but it is associated with an overgrowth of harmful microorganisms such as Gardnerella vaginalis or Prevotella which outnumber healthier types of vaginal bacteria including a. Bacterial vaginosis is the most common vaginal infection in women of childbearing age.

What is the cause. The overgrowth of these bacteria -- a condition called cytolytic vaginosis -- disrupts the normal vaginal environment causing it to become more acidic 1 2. Itâs normal to have some bacteria in the vagina but sometimes there are too many of certain types of bacteria.

The disturbed growth of vaginal bacteria is common and easily recurrent with women of 18-50 years old. The condition was formerly referred to as Gardnerella vaginitis after the bacteria that were believed to cause the condition. It is not a true bacterial infection but rather an imbalance of the bacteria that are normally present in the vagina.

However since there are a number of species of bacteria that naturally live in the vagina and can grow to excess or imbalance to cause the condition the name. Small amounts of these anaerobic bacteria and Gardnerella can normally be found in your vagina. Bacterial vaginosis BV is a condition that happens when there is too much of certain bacteria in the vagina.

Symptoms include an off-white or grey vaginal discharge that smells fishy In some women BV goes away without treatment in others antibiotics successfully treat this infection. Bacterial vaginosis BV is a very common condition caused by an overgrowth of bacteria in the vagina. Bacterial vaginosis BV is an abnormal vaginal condition that is characterized by vaginal discharge and results from an overgrowth of atypical bacteria in the vagina.

1 There is little inflammation and the disorder represents a disturbance of the vaginal microbial ecosystem rather than a true infection of tissues. Apart from infections an overgrowth of the normal vaginal bacteria is often found to be the cause of such a discharge. Vaginalis Mobiluncus spp genital mycoplasma and previously noncultivable anaerobes.

Bacterial vaginosis is not due to a single organism or species and is the result of massive overgrowth of mixed complex flora or microbiota including Bacteroides spp G. This changes the normal balance of bacteria in the vagina. What is Bacterial Vaginosis.

Bacterial vaginosis is the most common vaginal condition in women ages 15-44.

Fit Colon Cancer Screening

Fecal immunochemical test FIT The fecal immunochemical test FIT is a screening test for colon cancer. The idea behind this type of test is that blood vessels in larger colorectal polyps or cancers are often fragile and easily damaged by the passage of stool.

Bowel Cancer Screening In England Bowel Cancer Uk

FIT is the dominant screening test for colorectal cancer in most economically advanced countries and the results support the accuracy of widespread periodic FIT screening they added.

Fit colon cancer screening. If you received your fecal immunochemical test FIT kit from UCLA Health you likely received the Polymedco OC-Auto FIT kit pictured here. Printable instructions on how to complete the fecal immunochemical test FIT for colon cancer screening. Colonoscopy has long been the gold standard for colon cancer screening.

In one study of people who were at average risk of developing colon cancer and had no symptoms of colon problems the FIT-DNA test was more sensitive than the FIT test. The Faecal Immunochemical Test FIT is a preliminary test that detects the presence of small amounts of blood in faeces. FIT can be done in the comfort of your own home by following the instructions provided in your kit.

If gFOBT or FIT is the only type of colorectal cancer screening test performed experts generally recommend testing every year or two. The FIT-DNA test also referred to as the stool DNA test combines the FIT with a test that detects altered DNA in the stool. Regardless of the specific brand of FIT kit you received the steps required to complete the test are.

The observed trend toward a reduction of the protective effect of FIT screening with increasing interval since the last negative test also is consistent with previous findings. Felice Schnoll-Sussman a gastroenterologist at NewYork-Presbyterian. Annual use of the fecal immunochemical test FIT is a reliable way to screen for colon cancer new research shows.

The fecal immunochemical stool test FIT introduced in Nova Scotia in 2009 has been very effective. Fecal immunochemical test FIT One way to test for colorectal cancer is to look for occult hidden blood in the stool. FIT is an excellent option for colon cancer screening only if it is performed consistently on a yearly basis said Dr.

Your FIT colon cancer screening test results will show you if you are negative or positive for blood in your stool. The fecal immunochemical test FIT also called an immunochemical fecal occult blood test iFOBT is a newer kind of stool test that also detects occult hidden blood in the stool. This test is available in a simple kit that can be carried out in the comfort of your own home.

FIT detects blood in your stool poop which can be a sign of pre-cancer. This detection is important because it can be a sign of precancerous polyps or colorectal cancer. As of September 2017 the Colon Cancer Prevention Program has identified about 500 individuals with cancer and over 4000 have had precancerous polyps detected and removed as a.

Screening for colon cancer is an important part of early detection and treatment. The fecal immunochemical test FIT is a safe and painless test that checks your stool poop for tiny amounts of blood which can be caused by colorectal cancer or some pre-cancerous polyps growths in the colon or rectum that can turn into cancer over time. He or she will discuss colonoscopy with you and check if you are fit.

However the FIT-DNA test also was more likely to identify an abnormality when none was. A positive FIT result does not mean that you have colon cancerit simply means you need to share the results with your healthcare provider to discuss next steps which may include a colonoscopy screening. You can do this test at home and it only takes a few minutes.

According to the American Cancer Society American College of Physicians Centers for Disease Control and Prevention CDC National Colorectal Cancer Roundtable American Medical Association and many recently published reviews of FIT and CRC screening guidelines annual FIT tests are believed to decrease the incidence and mortality from CRC because randomized controlled trials using less. Second Generation FIT is the revolutionary test to aid in the detection of Colorectal Cancer that is fast accurate and easy to use. For this test you collect an entire bowel movement and send it to a lab where it is checked for cancer cells.

There are several different ways to do this which include colonoscopy sigmoidoscopy computed tomography and stool tests. FIT only detects human blood from the lower intestines. SCS distributes FIT kits without charge to eligible Singaporeans and Permanent Residents.

The screening test for colon cancer is called the Fecal Immunochemical Test FIT. It is also done once a year in the same way as a gFOBT. Now you can test for the same advanced colon cancer biomarker that hospitals labs and physicians offices do in the privacy of your own home with no.

One of these stool tests the fecal immunochemical test FIT can now be done from home which offers patients comfort and confidentiality. Now gastroenterologists say the quick inexpensive noninvasive FIT test is. A specialist screening practitioner SSP will talk with you about your screening result and answer any questions you have.

It tests for hidden blood in the stool which can be an early sign of cancer. The fecal immunochemical test FIT uses antibodies to detect blood in the stool.

Benefits Of Being A Veterinarian

Another benefit of this line of work is that veterinarians can develop a private practice and serve as their own boss. First veterinarians get to work with animals they love with the rest of their career or for life How much more rewarding is it to know that you have saved ones life.

The Intangible Benefits To Being A Veterinarian

Being a vet involves working with people just as much if not more as it involves working with their dogs cats or whatever species you are dealing with as a vet.

Benefits of being a veterinarian. What Are the Rewards of Being a Veterinarian. It is a benefit to be able to work with animals and see the progress they make in the journey to full recovery. Veterinarians are very helpful to animals and the animals owners.

While not unique to vets compassion fatigue is common among those who work in veterinary practice. Being able to save an animal in near death situations is one of the best feelings. Obviously becoming a veterinarian gives you the skills and knowledge you need to treat dogs cats and other animals and put them on the road to recovery.

Its a Rewarding Career. The veterinarian industry is only growing. Some veterinarians regularly save animals lives and help injured animals recover which is a dream come true for some.

Veterinarians take care of animals for as long as they need until they get better. However there are many benefits to all these costs. Other benefits include working with animals and people in a caring profession.

A veterinarian helps animals get better. Veterinarians take care of animals for as long as they need until they get better. The Benefits of Working as a Vet Tech So what exactly makes working as a veterinary technician so rewarding.

A veterinarian helps animals get better. But being a vet tech is a serious profession that requires training and licensing. Veterinarians can also make a lot of money but really thats just not it.

Being aware of the condition knowing the symptoms and the risk factors are an important part of being a vet. You would earn handsomely there are plenty of jobs and there is relative financial security. List of Pros of Being a Veterinarian.

This means that it is so important that we are able to communicate well and effectively with our clients building strong relationships as. Salary Benefits of being a vet. Of course it is fun to have the chance to be surrounded by animals and take cute pictures of yourself with puppies and kittens.

Youll have the chance to help animals. Average starting salary of 65000 Median annual salary of 91000 Top 10 earn over 150000 Excellent medica dental and vision coverage 2-4 weeks of paid vacation Paid sick leave Continuing education pay High demand for qualified vets. The whole purpose of being a veterinarian is to work with animals and bring them back to health.

Compassion fatigue Being exposed to heart-wrenching emotional situations and trauma regularly can and does take its toll emotionally. Benefits Of Being A Veterinarian 1197 Words 5 Pages. Since veterinarians involve health the career falls under health science.

Many professions are suffering from a scarcity of jobs. List of Pros of Being a Veterinarian. Since veterinarians involve health the career falls under health science.

I chose this career because the pay is more than enough to support a family and have enough for bills and fun. Veterinarians help animals with injuries illnesses diseases broken bones and any important accidents. What are the cons of a career in Veterinary Sciences.

- Being a veterinarian can pay you very well. - There is immense satisfaction in serving the helpless and the needy. - The course duration is too long.

You also have the ability to relieve the suffering of animals that have experienced traumatic injuries or chronic illnesses. Some veterinarians help animals all over the world. If you want to become a veterinary surgeon then you need to go for a 4-5 years program in veterinary sciences and animal husbandry.

One of the greatest benefits of a career in veterinary medicine such as a veterinary pathologist is the chance to promote the health and welfare of your patients. Veterinarians devote their careers to saving animals from life-threatening illnesses or injuries and helping ease the symptoms of arthritis diabetes. Well veterinarians have to help animal with important injuries.

How Long Does The Shingrix Vaccine Last

Zostavax zoster vaccine live shingles vaccine is available in a single dose and Shingrix recombinant zoster vaccine requires two doses administered two to six months apart. The immunity conferred from Shingrix for the prevention of shingles is thought to last longer and be more effective than the previous shingles vaccine Zostavax.

Duration Of Side Effects After Shingrix Administration

If the immune system does not react to HSV right away a vaccine cannot teach your body how to protect you.

How long does the shingrix vaccine last. We know that for most people the shingles vaccine protects for at least four years. Protection afforded by Shingrix also lasts longer. Some of the dosage forms listed on this page may not apply to the brand name Shingrix.

Shingrix is given as two 05-mL injections in your upper arm. If youve gotten either Shingrix or a COVID-19 vaccine in the last 14 days youll need to reach the 2-week mark before you get the other one. It lasts for approximately 5 years.

Side effects can last two or three days and the injection site in the upper arm can hurt. Intervals shorter than 5 years have not been studied. Food and Drug Administration in late 2017 is more likely to cause short-term side effects than either Zostavax or other vaccines for adults said Dr.

Shingrix is used to prevent herpes zoster virus shingles in people age 50 and older including people who previously received a live zoster vaccine. Protection from the Zostavax zoster vaccine live shingles vaccine lasts about five years. Studies confirmed that Shingrix was safe and immunogenic when administered 5 or more years after Zostavax.

Side effects are fairly common. Since your risk of shingles and PHN increases as you get older it is important to have strong protection against shingles in your older years. Shingrix approved by the US.

Though Shingrix was tested on some 16600 adults in clinical trials its real-world use has been limited. At this time the Centers for Disease Control and Prevention CDC doesnt recommend patients receive any booster dose after. Over time some vaccines protection begins to fade so may you.

Shingrix Prices from 204 15500. Even so it still lowers the risk of shingles by 21 percent. This document contains side effect information about zoster vaccine inactivated.

The two-dose vaccine is preferred because it is more effective. Shingrix Side Effects. Also still unclear is how long Shingrixs protection will last.

You can ask your provider when you should get the next dose of Shingrix after your first vaccination round. Currently the CDC recommends healthy people ages 50 and older get the Shingrix vaccine. Shingrix will not treat chickenpox shingles or nerve pain caused by shingles post-herpetic neuralgia.

However immune response doesnt. Also learn who may benefit the most from the vaccine. Most according to GlaxoSmithKline its manufacturer lasted less than three days.

Shingrix provides strong protection against shingles and protection stays above 85 for at least 4 years after your second dose. You receive the second dose two to six months after the first dose. However we expect that protection will last much longer.

Human studies of several vaccines have occurred in the last few years. The upside is Shingrix provides stronger protection against shingles a painful condition that wreaks. The research published in the Journal of Infectious Diseases shows that Shingrix offers protection for up to four years but Professor Cunningham believes it will last much longer.

The shingles vaccine is effective but it can cause side effects. Valacyclovir Prices from. The shingles vaccine is a one-shot vaccine and is available to people 50 years or older.

Shingrix protection remained high more than 85 in people 70 years and older throughout the four years following vaccination. Shingrix is more effective and likely longer lasting than the Zostavax vaccine in preventing shingles. Last updated on Nov 7 2020.

Overall protection against shingles rash was 976 after one year 92 after 2 years 879 after 3 years and 847 after 4. According to the CDC Shingrix protects you for at least 4 years after you get vaccinated. As per the recommendation of the CDC those who are 60 years or older should consider getting one dose of the shingles vaccine.

How Long Does Shingrix Last. The immune response from the shingles vaccine Shingrix is reported to be at least nine years based on the cellular response to the vaccine according to the CDC. However there are no data or theoretical concerns to indicate Shingrix would be less safe or effective when given less than 5 years after Zostavax.

Learn about the possible mild serious and long term side effects here. We dont know if a person gets vaccinated at the age of 50 if we should give them a booster every 10 years or every 15 to 20.

How To Know High Blood Pressure

High blood pressure also called hypertension is blood pressure that is higher than normal. If your blood pressure is higher than that you will be diagnosed with hypertension.

Hypertension Vs Hypotension The Highs And Lows Of Blood Pressure Mibluesperspectives

Your health care team will tell you if you need medicine for high blood pressure based on your blood pressure readings over a period of time.

How to know high blood pressure. Understanding these risk factors ca. Call 911 if someone you know takes blood pressure medication and experiences. If your blood pressure is 180120 millimeters of mercury mm Hg or higher and you have chest pain back pain numbness or weakness or a change in.

If your blood pressure ever. If your blood pressure is extremely. High blood pressure doesnt typically cause symptoms.

Elevated blood pressure is a systolic pressure ranging from 120 to 129 millimeters of mercury mm Hg and a diastolic pressure below 80 mm Hg. The most common type of cardiovascular disease high blood pressure causes our hearts to work harder by forcing blood to push against the walls of our arteries at an elevated level. If your systolic blood pressure is between 120 and 129 with a diastolic pressure under 80 you are considered to have elevated blood pressure and you should do something about it before it gets worse.

But this can happen in a hypertensive crisis when blood pressure is above 180120. Your blood pressure changes throughout the day based on your activities. Frequently there are no high blood pressure symptoms as blood pressure increases but some warning signs for very high blood pressure can include chest pains confusion headaches ear noise or buzzing irregular heartbeat nosebleeds tiredness or vision.

A number of factors and variables can put you at a greater risk for developing high blood pressure HBP or hypertension. If you do register a blood pressure reading of 12080 or over wait two to five minutes and recheck. If you use a home blood pressure monitor record or write down your readings.

Having blood pressure measures consistently above normal may result in a diagnosis of high blood pressure. Elevated blood pressure tends to get worse over time unless steps are taken to control blood pressure. 1 day agoHigh blood pressure is a deadly condition that increases the risk of heart attacks strokes and heart disease.

If its still high talk to your doctor to rule out hypertension. Well talk about what you should do in a minute. Most of the time high blood pressure doesnt cause headaches or nosebleeds.

But some people live their lives for years without even knowing that they have it. High blood pressure or hypertension occurs when your blood pressure increases to unhealthy levels. Hypertension is the leading cause of strokes and heart attack.

Sometimes people having high blood pressure may experience symptoms like headaches dizziness nose bleeds blurring of vision or difficulty in normal vision overall discomfort nausea and sometimes vomiting. However some people may have headachesespecially if their blood pressure skyrockets into the danger zonea condition known as high blood. A series of blood pressure readings below 9060 mm Hg accompanied by other symptoms Altered mental status including extreme confusion or loss of consciousness Inability to wake the person up.

Clinically known as hypertension high blood pressure can cause a host of problems if left untreated. Your blood pressure measurement takes into account how much blood is passing through your blood. Share your readings with your health care team so that you can make the best decision to manage your blood pressure together.

High blood pressure is considered to be 14090mmHg or higher or 15090mmHg or higher if youre over the age of 80 ideal blood pressure is usually considered to be between 9060mmHg and 12080mmHg.

Is Plan B 100 Effective

It may cause more side effects like nausea and vomiting too. Plan B is believed to act as an emergency contraceptive principally by preventing ovulation or fertilization by altering tubal transport of sperm andor ova.

Emergency Contraception San Francisco City Clinic

Plan Bs effectiveness isnt affected by alcohol tobacco or other drugs either.

Is plan b 100 effective. Out of 10 women that use it 2 will get pregnant. Plan B is FDA approved for use up to 72 hours after unprotected sex. In one of the studies the hormone in Plan B levonorgestrel was in a lower.

Although nothing is 100. Its definitely not 100 because if you are greater than 165 pounds that dose becomes ineffective. As Mary wrote Plan B doesnt work 100.

No not 100. According to research published in Contraception Plan B was shown to be less effective in women with a high BMI. Also all Plan B is is a massive dose of birth control pills.

According to Gersh Plan B is actually less effective than using birth control properly and ideally shouldnt become your standard practice for preventing pregnancy especially since the pill can run you 50 or more a pop. If you take the pill within 72 hours after youve had unprotected sex levonorgestrel can reduce the risk of pregnancy by up to 87 if taken as directed. Yes although this method isnt as effective as Plan B or Ella.

Its sole purpose is to block your brain from signaling the ovaries to release an egg or ovulate. The labeling on Plan B One-Step and its generics say that you should take it within 72 hours of unprotected sex and that its most effective the sooner you take it. Although morning-after pills arent 100 effective at preventing a pregnancy they can reduce the risk by 75-89 according to Planned Parenthood.

Yes Plan B must be taken within 72 hours but theres more to that story. The effectiveness varies and is highest if taken within the first 12-24 hours. Plan B is an emergency contraceptive that can prevent pregnancy up to 95 of the time by preventing or delaying ovulation if taken right after you have sex.

Plan B is 80 effective - just think about that. Nothing besides abstinence is. Its more like 7595 depending on where you are in your cycle.

If you take it within 72 hours you have up to an 89 chance. A levonorgestrel morning-after pill like Plan B One Step Take Action My Way Option 2 Preventeza AfterPill My Choice Aftera and EContra can lower your chance of getting pregnant by 75-89 if you take it within three days after unprotected sex. You can take Plan B and other levonorgestrel morning.

The Plan B should work for about 72 hours. If you take Plan B within 24 hours of unprotected sex its about 95 percent effective. If you take Plan B One-Step within 24.

Within the first 72 hours out of. It can be used up to 120 hours after but the further out from intercourse the less effective it will become says Bender. Although nothing is 100.

The best way to be sure where you are in your cycle is to check hormone levels. It could alter your period flow or. Next to that birth control pill is 99 effective.

Thats better than nothing but the only thing that is 100 effective is not having sex. Plan B has a 95 chance of preventing pregnancy if you take it within 24 hours. If you take it 72 hours afterward its still 89 percent effective.

If you have unprotected sex. Many researchers have further explained the notion that Plan B does not stop implantation from occurring is probably the reason that its not 100 percent effective at preventing an unintended pregnancy as well as why Plan B is less effective the longer you wait to use it. Anyway you can get pregnant probably within 3 days or 1 week of taking Plan B.

The manufacture may tout it prevents 7 out 8 pregnancies but realistically thats likely only with perfect timing. I would recommend you would be best to be on regular birth control. So please plan ahead if you dont want to have that baby just yet.

How effective is Plan B One-Step and other levonorgestrel morning-after pills. Your sister should have made you take a pregnancy test. Emergency contraceptive pills are not effective if a woman is already pregnant.

Plan B effectiveness hinges on when you take it.